AG-490 is a potent inhibitor of the JAK-2 tyrosine kinase. In acute lymphoblastic leukemia (ALL) cells, which abundantly express JAK-2, AG-490 dose-dependently inhibited DNA synthesis, blocked cell growth and induced apoptosis. At 5 µM, AG-490 almost com
Molecular Weight:
294.3
Purity:
98% (TLC)
CAS Number:
[133550-30-8]
Formula:
C17H14N2O3
Target:
JAK2
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