An irreversible inhibitor of cytokine-inducible IkappaBalpha phosphorylation (IC50=10 µM). In intact HUVECs it inhibits TNFalpha-induced phosphorylation and degradation of IkappaBalpha without affecting constitutive phosphorylation. Inhibition of IkappaBalpha phosphorylation and de
Molecular Weight:
249.3
Purity:
99% (TLC)
CAS Number:
[196309-76-9]
Formula:
C13H15NO2S
Target:
NF-kappaB
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