Potent and specific inhibitor of the protein kinase c-Raf (IC50=70nM). Has no significant effect on many other protein kinases tested (even at 50µM) with the exception of p38 (SAPK2a) (IC50=2µM) and SAPK2b (p38beta) (IC50=2µM). Induces a paradoxical >100-fo
Molecular Weight:
389.4
Purity:
95% (HPLC)
CAS Number:
[208260-29-1]
Formula:
C23H23N3O3
Target:
Raf, p38 alpha, p38 beta
* VAT and and shipping costs not included. Errors and price changes excepted