Tyrphostin AG 1296, 6,7-Dimethoxy-3-phenylquinoxaline
A potent inhibitor of PDGF receptor tyrosine kinase (IC50=1 µM). Also inhibits FGF receptor tyrosine kinase and c-kit. Induces apoptosis in a small-cell lung cancer cell line (H526).
Molecular Weight:
266.3
Purity:
98% (TLC)
CAS Number:
[146535-11-7]
Formula:
C16H14N2O2
Target:
PDGF receptor, FGF receptor, c-Kit
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