Potent inhibitor of CDK1/cyclin B (IC50=400nM). Also inhibits CDK2/cyclin A (IC50=680nM) , CDK5 (IC50=850nM) and with much less effect other kinases. More recently, kenpaullone has been found to be a useful GSK-3beta inhibitor (IC50=23nM). Induces pluripote
Molecular Weight:
327.2
Purity:
98% (TLC)
CAS Number:
[142273-20-9]
Formula:
C16H11BrN2O
Target:
CDK1, CDK2, CDK5, GSK-3beta
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