Selective, reversible and ATP-competitive inhibitor of IKK2 (IC50=11.2µM). Does not inhibit other IKK isoforms or other serine/threonine or tyrosine kinases. Inhibits transcription of NF-kappaB dependent genes in IL-1beta-induced rheumatoid arthritis-derived sy
Molecular Weight:
224.3
Purity:
98% (TLC)
CAS Number:
[354812-17-2]
Formula:
C9H8N2OS2
Target:
NF-kappaB, IKK beta
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