Highly potent inhibitor of VEGFR-1 (IC50=130nM), VEGFR-2 (IC50=23nM) and VEGFR-3 (IC50=18nM). At higher concentrations it inhibits PDGFR-beta (640nM), c-Kit (236nM) and CSF-1R (380nM).
Molecular Weight:
371.4
Purity:
98% (HPLC)
CAS Number:
[269390-77-4]
Formula:
C20H16F3N3O
Target:
VEGFR-1, VEGFR-2, VEGFR-3
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