A potent and selective inhibitor of insulin-like growth factor 1 receptor (IGF-1R, IC50=6 nM). It efficiently blocks IGF-1R activity, reduces pAKT and pERK1/2, induces apoptosis in IGF-1R-positive tumor cells and causes complete tumor regression in xenog
Molecular Weight:
414.4
Purity:
98% (HPLC)
CAS Number:
[477-47-4]
Formula:
C22H22O8
Target:
IGF-1 receptor
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