BML-277 is a highly selective inhibitor of Chk2 (IC50=15nM). It displays potent radioprotective activity and prevents apoptosis of human T cells subjected to ionizing radiation (EC50= 3-7.6µM). Useful tool for dissecting the role of Chk2 in cellular sign
Molecular Weight:
363.8
Purity:
98% (HPLC)
CAS Number:
[516480-79-8]
Formula:
C20H14ClN3O2
Target:
Chk2
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