Novel inhibitor of NAD(P)H oxidase (Nox). In vascular smooth muscle cells VAS-2870 completely abolished PDGF-mediated NAD(P)H oxidase activation and ROS production (100% at 10µM). It inhibits PDGF-induced chemotaxis but not proliferation of VSMC. In mous
Molecular Weight:
360.4
Purity:
98% (HPLC)
CAS Number:
[722456-31-7]
Formula:
C18H12N6OS
Target:
NADPH oxidase
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