Endogenous [1] ligand for the CB1 receptor (CB1: Ki=52nm, CB2: Ki=1930nm [2]) and TRPV1 (Ki=5.78µM [3,4]). Inhibits NF-kappaB activation through direct binding to IKKbeta [5] and induces apoptosis independently of cannabinoid or vanilloid receptors [6]. Activat