Potent inhibitor of farnesyltransferase in isolated enzyme assays (IC50=55nM) but is inactive in whole cells. Inhibition of farnesyltransferase is selective over geranylgeranyltransferase I and II (IC50=92µM and 34µM respectively).
Molecular Weight:
370.4
Source:
Synthetic.
Purity:
98% (TLC)
CAS Number:
[148796-51-4]
Formula:
C19H32O4 . 2Na
Target:
Farnesyltransferase
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