CITCO is a novel potent and selective agonist for the human orphan nuclear receptor CAR (constitutive androstane receptor). CITCO displayed an EC50 of 49 nM in a CAR FRET assay and showed 50-fold selectivity for CAR over PXR. CITCO displayed no activity
Molecular Weight:
436.7
CAS Number:
[338404-52-7]
Formula:
C19H12Cl3N3OS
Target:
Constitutive androstane receptor
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