CP-31398 restores mutant p53 tumor suppressor function in vitro without affecting p53 homologs p63 and p73, and in vivo inhibiting UVB-induced skin carcinogenesis in mice. Stabilization of p53 inhibits ubiquitination without altering phosphorylation at S
Molecular Weight:
435.4
Source:
Synthetic.
Purity:
98% (HPLC)
CAS Number:
[259199-65-0]
Formula:
C22H26N4O . 2HCl
Target:
p53
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