Paxilline is an indole alkaloid isolated from Penicillium paxilli. It is a selective and reversible blocker of the smooth muscle high conductance Ca2+-activated K+ (maxi-K) channel (70% block at 10 nM). In neutrophils, Paxilline blockage of BKCa channels
Molecular Weight:
435.6
Purity:
97% (HPLC)
CAS Number:
[57186-25-1]
Formula:
C27H33NO4
Target:
Calcium-activated potassium channel, IP3 receptor
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