Most potent member of the ginkgolide family of PAF antagonists. Ginkgolide B accelerates PAF hydrolysis by promoting PAF-AH I alpha2 homodimer activity. Inhibits PAF-induced PMNL chemotaxis (IC50=490 nM). Orally effective against PAF-induced bronchospasm.
Molecular Weight:
424.4
Purity:
90% (HPLC)
CAS Number:
[15291-77-7]
Formula:
C20H24O10
Target:
PAF receptor
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