Ingenol is a diterpenoid related to phorbol. Activates protein kinase C (PKC) and competes with [3H]phorbol dibutyrate for binding to PKCalpha (Ki for binding=240 nM). Induces apoptosis. Anticancer agent. Shows potent antileukemic activity in the P388 mouse
Molecular Weight:
556.7
Purity:
97%
CAS Number:
[59086-90-7]
Formula:
C34H36O7
Target:
PKC
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