A potent, selective, orally active leukotriene D4 antagonist. Ki=2.1 nM for inhibition of [3H]-LTD4 binding to human lung membranes. Competitively antagonizes contractions of guinea pig trachea and ileum and human trachea induced by LTD4. Blocks LTD4 and
Molecular Weight:
537
Purity:
90% (HPLC)
CAS Number:
[115104-28-4]
Formula:
C26H26ClN2O3S2 . Na
Target:
Leukotriene D4 receptor, Prostanoid receptor
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