Produced in E. coli. cDNA encodes residues identical to Asn120-His404 (C-terminus) at Genbank Accession No. M87507, except for an Asp381 to Glu change, introduced to stabilize the enzyme against autoproteolysis.
Purity:
Purified by multi-step chromatography.
Form:
Liquid. In 50mM HEPES, pH 7.4, containing 100mM sodium chloride, 0.5% CHAPS, 1mM EDTA, 10% glycerol and 10mM DTT.
Target:
Caspase| Caspase-1| Caspase| Caspase-1
Application Notes:
Useful tool to study enzyme regulation and kinetics, cleave target substrates, screen for inhibitors.
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