ADAM17 (catalytic domain) (human), (recombinant) (His-tag)

Product Overview

• Article Name: ADAM17 (catalytic domain) (human), (recombinant) (His-tag)
• Biozol Catalog Number: ENZ-BML-SE268-0010
• Supplier Catalog Number: BML-SE268-0010
• Alternative Catalog Number: ENZ-BML-SE268-0010-10
• Manufacturer: Enzo Life Sciences
• Category: Proteine/Peptide
• Alternative Names: TACE, A disintegrin and metalloproteinase 17, Tumor necrosis factor-alpha-converting enzyme

Product Description

ADAM17 (catalytic domain) (human), (recombinant) (His-tag)

Product Properties

• Molecular Weight: ~30.5kDa (calculated), ~36kDa doublet (SDS-PAGE)
• UniProt: P78536
• Source: Produced in insect cells. Produced in a baculovirus expression system.
• Purity: Purified by multi-step chromatography.
• Form: Liquid. In 22.5mM TRIS, pH 7.5, containing 4.5µM ZnCl2, 0.0045% Brij-35 and 10% glycerol.
• Sequence: Recombinant glycosylated catalytic domain (aa Pro18-Val477) of ADAM17/TACE (A disintegrin and metalloproteinase 17, Tumor necrosis factor-alpha-converting enzyme), cloned from human cDNA (NM_003183), secreted as mature, active enzyme from insect cells, an
• Target: ADAM| ADAM

Application Notes

• Application Notes: Useful tool to study enzyme kinetics, cleave target substrates, screen inhibitors.