A fungal metabolite produced by Fusarium moniliforme. Mycotoxin. Inhibits sphinganine N-acyl-transferase(ceramide synthase)(IC50=0.1µM). Inhibits de novo sphingolipid biosynthesis (IC50=0.7µM for sphingomyelin labeling by [3H]sphinganine, cultured cerebe
Molecular Weight:
721.8
Purity:
98% (HPLC)
CAS Number:
[116355-83-0]
Formula:
C34H59NO15
Target:
GSK-3beta, Akt, Ceramide synthase
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