Antibiotic. Activates JNK/SAPKs, p38 and MAP kinases but not ERKs leading to the phosphorylation of S6, histone H3 and HMG-14 and the induction of the immediate-early genes c-fos and c-jun. Induces apoptosis in the human monoblastoid cell line. Used at 3
Molecular Weight:
265.3
Source:
Isolated from Streptomyces griseolus.
Purity:
97% (TLC)
CAS Number:
[22862-76-6]
Formula:
C14H19NO4
Target:
MAPK, Jnk, p38
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