AACOCF3 is a trifluoromethylketone derivative of arachidonic acid. It is a selective inhibitor of human cytosolic PLA2 and Ca2+-independent PLA2 (iPLA2, IC50=15 µM). It is active in intact platelets and U937 cells (IC50=8 µM). It also inhibits fatty acid
Molecular Weight:
356.5
Purity:
98% (TLC)
CAS Number:
[149301-79-1]
Formula:
C21H31F3O
Target:
PLA2 (Ca2+-independent), PLA2 (cytosolic)
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