Potent inhibitor of Tankyrase 1 (IC50=11nM) and Tankyrase 2 (IC50=4nM). Inhibition of tankyrase promotes stabilization of axin resulting in beta-catenin degradation and Wnt signalling disruption. Inhibits proliferation of the µ-catenin-dependent colon carci
Molecular Weight:
312.3
Purity:
98% (HPLC)
CAS Number:
[284028-89-3]
Formula:
C14H11F3N2OS
Target:
PARP5a
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