GSK-3beta inhibitor (IC50=53nM (enzymatic), 3.8µM (cellular)). The compound significantly increases beta-catenin levels, leads to TCF-induction and promotes neuronal differentiation in human neural progenitor cells via activation of canonical Wnt signaling.
Molecular Weight:
377.4
Purity:
98% (HPLC)
CAS Number:
[1129669-05-1]
Formula:
C22H20FN3O2
Target:
GSK-3beta
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