The HIV protease (PR) hydrolyzes polyproteins of HIV virus into functional protein products that are essential for its assembly and subsequent activity. This maturation process occurs as the virion buds from the host cell. HIV protease inhibitors are used in the treatment of patients with AIDS and were considered the first breakthrough in over a decade of AIDS research. HIV protease inhibitors can lower the viral load carried by AIDS patents.
Clonality:
Monoclonal
Concentration:
1 mg/ml
Clone Designation:
[1696]
Isotype:
Mouse IgG1
Buffer:
Phosphate buffered saline (PBS), pH 7.4
Storage:
2°C to 8°C
Target:
HIV-1/HIV-2 protease
Antibody Type:
Monoclonal Antibody
Application Notes:
Functional application: The antibody 1696 strongly inhibits the enzyme activity of HIV-1 and HIV-2 proteases. Western blotting: Recommended dilution: 0.5 µg/ml.
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