Anti-Hu CD10 Purified, Clone: [LT10], Monoclonal

Catalog Number: EXB-11-413-C100
Article Name: Anti-Hu CD10 Purified, Clone: [LT10], Monoclonal
Biozol Catalog Number: EXB-11-413-C100
Supplier Catalog Number: 11-413-C100
Alternative Catalog Number: EXB-11-413-C100
Manufacturer: EXBIO
Category: Antikörper
Application: FC
Species Reactivity: Human
Immunogen: mouse NALM-6 leukemia pre-B cell line (tissue/cell preparation)
CD10 (neutral endopeptidase - NEP, common acute lymphocytic leukemia antigen - CALLA, membrane metallo-endopeptidase - MME, enkefalinase) is a 100-kDa cell surface zinc metalloprotease, cleaving peptide bonds on the N-terminus of hydrophobic amino acids and inactivating multiple physiologically active peptids. CD10 is expressed on various normal cell types, including lymphoid precursor cells, germinal center B lymhocytes, and some epithelial cells, and its expression level serves as a marker for diagnostics of many carcinomas. CD10 is also a differentiation antigen for early B-lymphoid progenitors in the B-cell differentiation pathway and has a key role in regulation of growth, differentiation and signal transduction of many cellular systems.
Clonality: Monoclonal
Concentration: 1 mg/ml
Clone Designation: [LT10]
Isotype: Mouse IgG1
Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage: 2°C to 8°C
Target: CD10
Antibody Type: Monoclonal Antibody
Application Notes: Flow cytometry: Recommended dilution: 1-4 µg/ml.