Anti-Clathrin Heavy Chain Purified, Clone: [BF-06], Monoclonal
Biozol Catalog Number:
EXB-11-526-C100
Supplier Catalog Number:
11-526-C100
Alternative Catalog Number:
EXB-11-526-C100
Manufacturer:
EXBIO
Category:
Antikörper
Application:
ELISA, FC, ICC, IP, WB
Species Reactivity:
Bovine, Human, Mouse, Porcine, Rat
Clathrin is a submembrane protein that polymerizes into coat-like lattices, which results in membrane invagination. The basic oligomers are composed of three clathrin heavy chain (180 kDa) and three light chain (30 kDa) subunits and the process of polymerization is dynamically regulated by the light chains. Interaction of clathrin with the plasma membrane is mediated by adaptor proteins (AP1-4) specific for different cellular compartments. Another proteins, such as endophilin, epsin and amphiphysin are involved in membrane invagination and clathrin rearrangements. Finally, dynamin functions at the fission stage of clathrin-mediated endocytosis.
Clonality:
Monoclonal
Concentration:
1 mg/ml
Clone Designation:
[BF-06]
Isotype:
Mouse IgM
Buffer:
Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
