The p53 family of proteins includes three members, p53, p63, and p73. The protein p63 is encoded by TP63 gene, which gives rise to protein isoforms with different properties and functions due to the presence (TAp63) or absence (deltaNp63) of an N-terminal transactivation domain. Immunohistochemistry of p63 has a clinical relevance for certain tumor types, but investigations have been hampered by a lack of well characterized antibodies that are specific for p63 and do not cross-react with the related p53 and p73 proteins.
Clonality:
Monoclonal
Concentration:
1 mg/ml
Clone Designation:
[PANp63-6.1]
Isotype:
Mouse IgG1
Buffer:
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Target:
p63
Antibody Type:
Monoclonal Antibody
Application Notes:
Western blotting: Recommended dilution: 1 µg/ml
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