The p53 family of proteins includes three members, p53, p63, and p73. The protein p73 is encoded by TP73 gene, which gives rise to protein isoforms with different properties and functions due to the presence (TAp73) or absence (deltaNp73) of an N-terminal transactivation domain. Investigations have been hampered by a lack of well characterized antibodies that are specific for p73 and do not cross-react with the related p53 and p63 proteins, as well as a lack of antibodies that specifically recognize either the TAp73 or deltaNp73 variants. We are introducing now such a set of antibodies.
Clonality:
Monoclonal
Concentration:
1 mg/ml
Clone Designation:
[DNp73-1.1]
Isotype:
Mouse IgG1
Buffer:
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Target:
deltaNp73
Antibody Type:
Monoclonal Antibody
Application Notes:
Western blotting: Recommended dilution: 1 µg/ml
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