CD200R is a transmembrane glycoprotein, expressed on the surface of myeloid cells. Its interaction with CD200 leads in these cells to a downregulatory signal. This interaction may control myeloid function in a tissue-specific manner. Alternative splicing of CD200R gene results in multiple transcript variants. These isoforms may play a role in differentiation, e.g. regards tolerogenic dendritic cells. Besides myeloid cells, CD200R can be found also on a T cell subset.
Clonality:
Monoclonal
Concentration:
1 mg/ml
Clone Designation:
[OX-108]
Isotype:
Mouse IgG1 kappa
Buffer:
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Target:
CD200R
Antibody Type:
Monoclonal Antibody
Application Notes:
Flow cytometry: Recommended dilution: 2-5 µg/ml.
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