CD49f (alpha 6 integrin) is a type I transmembrane glycoprotein, which noncovalently associates with CD29 (beta 1 integrin) to form VLA-6, and with CD104 (beta 4 integrin) to form alpha6/beta4 integrin complex. CD49f is expressed on platelets, megakaryocytes, monocytes, T cells and thymocytes. It is widely expressed on many cultured adherent cell lines and on epithelia in non-lymphoid tissues. It is important for adhesion to laminins, invasin, and merosin, hence also for cell migration, embryogenesis, metastasis, formation of hemidesmosomes in epithelia, and other processes.
Clonality:
Monoclonal
Concentration:
1 mg/ml
Clone Designation:
[GoH3]
Isotype:
Rat IgG2a
Buffer:
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Target:
CD49f
Antibody Type:
Monoclonal Antibody
Application Dilute:
Flow cytometry: Recommended dilution: 1-4 µg/ml.
Application Notes:
Flow cytometry: Recommended dilution: 1-4 µg/ml.
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