CD156c is a type I transmembrane glycoprotein with a zinc-dependent metalloprotease activity. It serves as an endopeptidase of broad specificity, which is expressed mainly in thymus, liver, and muscles. Its expression can be induced in inflamed central nervous system, and in arthritic tissues. CD156c is involved in multiple sclerosis-associated myelin degradation. It also solubilizes various membrane proteins, including CD23, CD44, CD126, CD171, ephrin-A2, and other.
Clonality:
Monoclonal
Concentration:
1 mg/ml
Clone Designation:
[11G2]
Buffer:
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Target:
CD156c
Application Notes:
Flow cytometry: Recommended dilution: 1-5 µg/ml, extracellular and intracellular staining.
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