CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade. Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can still regulate complement when bound to CD97. In tumours, besides protection agains complement, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis.
Clonality:
Monoclonal
Concentration:
1 mg/ml
Clone Designation:
[MEM-118]
Isotype:
Mouse IgM
Buffer:
Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
Storage:
2°C to 8°C
Target:
CD55
Antibody Type:
Monoclonal Antibody
Application Notes:
Flow cytometry: Recommended dilution: 5-8 µg/ml.
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