CD58 (LFA-3) is an immunoglobulin family adhession molecule expressed by both hematopoietic and non-hematopoietic cells (often on antigen presenting cells) and serving as ligand of CD2. This interaction is important for T cell-mediated immunity. CD58 is expressed in transmembrane form and in GPI-anchored form, the later is constitutively associated with protein kinases whereas the transmembrane form activates kinase activity upon triggering. CD58 is a powerful tool for detection of minimal residual disease in acute lymphocytic leukemia, and for evaluation of liver damage related with hepatitis B.
Clonality:
Monoclonal
Concentration:
1 mg/ml
Clone Designation:
[MEM-63]
Isotype:
Mouse IgG1
Buffer:
Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
Storage:
2°C to 8°C
Target:
CD58
Antibody Type:
Monoclonal Antibody
Application Notes:
Flow cytometry: Recommended dilution: 2-12 µg/ml.
* VAT and and shipping costs not included. Errors and price changes excepted
