A cell suspension containing osteoclasts from osteoclastomas
Conjugation:
Biotin
CD51/CD61 (integrin alpha5beta3), also known as osteoclast functional antigen, serves as a vitronectin receptor, and binds also to fibronectin, fibrinogen, thrombospondin, osteopontin, collagen, and von Willebrand factor. Expression of this antigen increases with melanoma progression. In healthy individuals CD51/CD61 is expressed mainly on osteoclasts, placenta, and endothelial cells, at lower levels on platelets and macrophages.
Clonality:
Monoclonal
Concentration:
1 mg/ml
Clone Designation:
[23C6]
Buffer:
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Target:
CD51/CD61
Application Notes:
Flow cytometry: Recommended dilution: 1-5 µg/ml
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