Anti-Hu CD53 FITC, Clone: [MEM-53], Monoclonal

Product Overview

• Article Name: Anti-Hu CD53 FITC, Clone: [MEM-53], Monoclonal
• Biozol Catalog Number: EXB-1F-227-T100
• Supplier Catalog Number: 1F-227-T100
• Alternative Catalog Number: EXB-1F-227-T100
• Manufacturer: EXBIO
• Category: Antikörper
• Application: FC
• Species Reactivity: Human
• Immunogen: Leukocytes of pacient suffering from a LGL-type leukemia.
• Conjugation: FITC

Product Description

CD53 is a tetraspanin family transmembrane glycoprotein expressed in the lymphoid-myeloid lineage. This molecule has been reported to form complexes with other leukocyte surface proteins such as CD2, CD19, CD21, MHC II, VLA-4 or tetraspanins CD37, CD81 and CD82, thus probably modulating various signaling processes. CD53 is involved in radioresistancy of tumour cells and its triggering has anti-apoptotic effect. In thymus, CD53 is up-regulated in response to positive selection signals during T cell development, and is strongly expressed upon macrophage exposure to bacterial lipopolysaccharide, whereas stimulation of neutrophils results in down-regulation of CD53 expression.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [MEM-53]
• Isotype: Mouse IgG1
• Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Storage: 2°C to 8°C
• Target: CD53
• Antibody Type: Monoclonal Antibody

Application Notes

• Application Dilute: Flow cytometry: The reagent is designed for analysis of human blood cells using 20 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
• Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 20 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.