Anti-Hu CD80 FITC, Clone: [MEM-233], Monoclonal

Product Overview

• Article Name: Anti-Hu CD80 FITC, Clone: [MEM-233], Monoclonal
• Biozol Catalog Number: EXB-1F-287-T100
• Supplier Catalog Number: 1F-287-T100
• Alternative Catalog Number: EXB-1F-287-T100
• Manufacturer: EXBIO
• Category: Antikörper
• Application: FC
• Species Reactivity: Human
• Immunogen: Extracellular domain of human CD80 fused to human IgG1(Fc)
• Conjugation: FITC

Product Description

CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet, there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [MEM-233]
• Isotype: Mouse IgG1
• Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Storage: 2°C to 8°C
• Target: CD80
• Antibody Type: Monoclonal Antibody

Application Notes

• Application Dilute: Flow cytometry: The reagent is designed for analysis of human blood cells using 20 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
• Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 20 µl reagent / 100 µl of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.