Pooled lipid raft fraction isolated from RBL-2H3 cells
PLSCR1 (phospholipid scramblase 1) is a multiply palmitoylated endofacial plasma membrane protein containing several SH3 and WW domain binding motives. In the plasma membrane, PLSCR1 plays a role in transbilayer lipid redistributions and signal transduction. Nonpalmitoylated PLSCR1, however, is able to be transported into the nucleus and bind DNA. PLSCR1 potentiates the antiviral activity of interferon and its expression is highly induced by interferons and growth factors.
Clonality:
Monoclonal
Clone Designation:
[13A6 TEC-23]
Isotype:
Mouse IgG2a
Buffer:
Stabilized with 15mM sodium azide.
Storage:
2°C to 8°C
Target:
PLSCR1
Antibody Type:
Monoclonal Antibody
Application Notes:
Western blotting: Recommended dilution: 1 µg/ml, positive control: RBL (rat basophilic leukemia) cell line, both reducing and non-reducing conditions.Flow cytometry: Intracellular staining.
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