Chemical Name: 2,2-Dimethyl-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester butanoic acid. Alternate Names: Mevinolin
HMG-CoA reductase inhibitor
Molecular Weight:
418.58
Purity:
98% by TLC, NMR (Conforms)
Form:
White solid
CAS Number:
[79902-63-9]
Formula:
C25H38O5
Application Notes:
A synthetic analog of lovastatin. Blocks cholesterol and isoprenoid biosynthesis via inhibition of HMG-CoA reductase1,2. Induces apoptosis in various cell lines. Causes cell cycle arrest in early G1 phase. Clinically useful antilipemic agent3.
10-1018
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