Imatinib mesylate, CAS [[220127-57-1]]

Product Overview

• Article Name: Imatinib mesylate, CAS [[220127-57-1]]
• Biozol Catalog Number: FBM-10-1060
• Supplier Catalog Number: 10-1060
• Alternative Catalog Number: FBM-10-1060-20MG, FBM-10-1060-100MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide methanesulfonate. Alternate Names: Gleevec, STI571

Product Description

BCR-ABL inhibitor

Product Properties

• Molecular Weight: 493.62 96.11
• Purity: 98% by TLC, NMR (Conforms)
• Form: White solid
• CAS Number: [220127-57-1]
• Formula: C29H31N7O CH3SO3H

Application Notes

• Application Notes: Imatinib is a tyrosine kinase inhibitor specific for abl (IC50 = 0.038 µM)1, PDGF-R (IC50 = 0.3 µM)1 and c-kit (IC50 = 0.1 µM)2. It is a clinically useful anti-cancer drug approved for the treatment of chronic myelogenous leukemia, gastrointestinal stromal tumors as well as several other cancers.