Chemical Name: Ethyl 2-(4-(-2-((1S, 3S, 5S)-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)-2,6-dioxopiperidin-1-yl)acetate
FKBP12 inhibitor
Molecular Weight:
367.44
Purity:
99% by TLC, NMR Conforms
Form:
White solid
Formula:
C19H29NO6
Application Notes:
FKBP12 inhibitor (IC50=4.4 µM) with neuroregenerative properties. Does not inhibit protein synthesis (as does cycloheximide).1 Mimics a helical peptide in target proteins for binding to the immunophillin Mip homolog, BpML1 (Burkholderia pseudomallei Mip-like protein 1).2
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