Rapamycin, CAS [[53123-88-9]]

Product Overview

• Article Name: Rapamycin, CAS [[53123-88-9]]
• Biozol Catalog Number: FBM-10-1104
• Supplier Catalog Number: 10-1104
• Alternative Catalog Number: FBM-10-1104-10MG,FBM-10-1104-50MG,FBM-10-1104-10MM/1MLDMSO
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Sirolimus, AY-22989, WY-090217, NSC-226080, Rapamune

Product Description

mTOR inhibitor

Product Properties

• Molecular Weight: 914.17
• Purity: 98% NMR Conforms
• Form: White solid
• CAS Number: [53123-88-9]
• Formula: C51H79NO13

Application Notes

• Application Notes: Clinically useful immunosuppressant. Inhibits the response to interleukin-2 blocking activation of T- and B-cells.1 Rapamycin forms a complex with cytosolic FK-binding protein 12 (FKB12) that binds to mTOR Complex1(mTORC1) inhibiting the mammalian target of rapamycin (mTOR).2 Also binds to mTORC2 leading to decreased glucose tolerance and insensitivity to insulin.3 Induces autophagy.4