Chemical Name: 4-(3-Phenoxybenzylamino)phenylpropionic acid
GPR40 agonist
Molecular Weight:
347.42
Purity:
>98% [TLC 40% ethanol in hexanes, Rf = 0.31]
Form:
Off-white solid
CAS Number:
[885101-89-3]
Formula:
C22H21NO3
Application Notes:
Selective agonist at the free fatty acid receptor, FFA1/4, (GPR40 and GPR120).1 Displays anti-allodynic and anti-hyperalgesic effects in mouse inflammatory and neuropathic pain models.2 Inhibits LPA-induced proliferation of DU145 and PC-3 cells.3 Decreases hepatic lipid accumulation in a high fat diet steatosis mouse model.4 Promotes brown adipose tissue thermogenesis.5
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