Chemical Name: (11beta,16alpha)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
Apoptosis inducing glucocorticoid
Molecular Weight:
392.46
Purity:
98% NMR conforms
Form:
White solid
CAS Number:
[50-02-2]
Formula:
C22H29FO5
Application Notes:
A synthetic anti-inflammatory glucocorticoid. Induces apoptosis in a variety of cell types1,2. It inhibits proliferation of A549 human lung adenocarcinoma cells and induces cell surface expression of lipocortin-13. Induces osteogenic differentiation of human mesenchymal stem cells4. Induces indoleamine-2,3-dioxygenase (IDO) and exerts IDO-dependent protection in a model of allergic airway inflammation5. Resets and synchronizes circadian clock in cultured cells6.
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