Chemical Name: 8-Cholrodibenz(Z)[b,f]oxazepine-10(11H)-carboxylic acid 2-[1-oxo-3-(4-pyridinyl)propyl]hydrazide hydrochloride
Prostaglandin E (EP1) antagonist
Molecular Weight:
459.34
Purity:
98% by TLC, NMR (Conforms)
Form:
White solid
CAS Number:
[146033-02-5]
Formula:
C22H19ClN4O3 HCl
Application Notes:
Prostaglandin E2 (EP1 receptor) antagonist (pA2=6.5, guinea pig ileum muscle strip assay )1,4. Possesses analgesic activity in vivo (rodent ED50= 6.8 mg/kg)1,2,4. Does not inhibit COX11 and does not block PGE1 induced hyperalgesia3.
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