Chemical Name: N-(4-Chlorophenyl)-2-phenyl-N-(1-propan-2-ylpiperidin-4-yl)acetamide hydrochloride
Voltage-gated sodium channel blocker
Molecular Weight:
407.38
Purity:
98% by HPLC, NMR (Conforms)
Form:
powder
CAS Number:
[58934-46-6]
Formula:
C22H27ClN2O HCl
Application Notes:
Voltage-gated Na+ channel blocker.1 Protects murine cultured cortical neurons from injury induced by oxygen-glucose deprivation.2 Acts at the ouabain binding site of guinea pig cardiac Na+/K+ ATPase and inhibits the enzyme (IC50 = 34 µM).3
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