Xanthohumol, CAS [[6754-58-1]]

Product Overview

• Article Name: Xanthohumol, CAS [[6754-58-1]]
• Biozol Catalog Number: FBM-10-1188
• Supplier Catalog Number: 10-1188
• Alternative Catalog Number: FBM-10-1188-5MG,FBM-10-1188-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

VCP inhibitor / Autophagy inhibitor

Product Properties

• Molecular Weight: 354.41
• Purity: 98% by TLC, NMR (Conforms)
• Form: Yellow solid
• CAS Number: [6754-58-1]
• Formula: C21H22O5

Application Notes

• Application Notes: Binds to the N-terminal domain of valosin-containing protein (VCP), an essential protein for autophagosome maturation. Xanthohumol inhibits the function of VCP thereby impairing autophagosome maturation and resulting in accumulation of the microtubule-associated protein 1 light chain 3-II (LC3-II)1. Impairs prostate cancer cell growth and proliferation2. Cell permeable.