2-APB, CAS [[524-95-8]]
Catalog Number:
FBM-10-1212
| Article Name: |
2-APB, CAS [[524-95-8]] |
| Biozol Catalog Number: |
FBM-10-1212 |
| Supplier Catalog Number: |
10-1212 |
| Alternative Catalog Number: |
FBM-10-1212-100MG, FBM-10-1212-250MG |
| Manufacturer: |
Focus Biomolecules |
| Category: |
Biochemikalien |
| Alternative Names: |
Chemical Name: 2-Aminoethoxydiphenyl borate |
| Molecular Weight: |
225.1 |
| Purity: |
98% by TLC, NMR Conforms |
| Form: |
White solid |
| CAS Number: |
[524-95-8] |
| Formula: |
C14H16BNO |
| Application Notes: |
An IP3 receptor antagonist (IC50=42 µM).1 Inhibits store-operated Ca2+ channels at high concentrations (50 µM) but stimulates at low concs. (<10 µM).2 Modulates TRP channels, blocking TRPC1, TRPC3, TRPC5, TRPC6, TRPV6, TRPM3, TRPM7, TRPM8, TRPP2 and at higher concentrations, activating TRPV1, TRPV2, TRPV3.3,4 Also inhibits selected GAP junction subtypes.5 |
