Chemical Name: 2-Methyl-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester butanoic acid. Alternate Names: Mevinolin
HMG-CoA reductase inhibitor
Molecular Weight:
404.55
Purity:
98% by TLC, NMR (Conforms)
Form:
White solid
CAS Number:
[75330-75-5]
Formula:
C24H36O5
Application Notes:
Blocks cholesterol and isoprenoid biosynthesis via inhibition of HMG-CoA reductase (Ki=1nM for acid form).1,2 Induces apoptosis in various cell lines.3 Causes cell cycle arrest in early G1 phase.4 Clinically useful antihyperlipemic agent.5 Cell permeable
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